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Why Your Brain Predicts Your Life Before You Live It
The science of how expectations reshape your reality.

Hi there,
In the late 1970s, healthy young men began dying in their sleep. No warning. No chronic illness. Just a final gasp, a struggle for breath—and then, gone. Just like that.
Health officials were baffled. No toxins. No heart defects. Nothing.
Yet the deaths kept coming. So many, in fact, that this mysterious phenomenon—Sudden Unexpected Nocturnal Death Syndrome—became the leading cause of mortality among a specific group of young men.
Authorities were stumped. Until medical anthropologist Shelley Adler made a chilling discovery: every victim came from the same region of Laos and shared a deep belief in a night demon said to sit on your chest and suffocate you in your sleep.
Even in the U.S., their belief in traditional folklore stayed with them. And it turned out, the fear alone was enough to trigger fatal heart attacks.
Their minds imagined terror.
Their bodies obeyed.
Wild, right? 🤯
When Beliefs Alter Biology
But that kind of thing only happens to other people… right?
We like to think we’re immune. Too modern. Too rational. Too educated to fall for ghost stories or phantom illnesses.
But science says otherwise.
Over just 10 years, researchers noticed a massive spike in self-reported gluten intolerance in the U.S.—up from 3% to nearly 30%.
Gluten-free menus exploded. Wellness blogs caught fire. But researchers had a question: Had human biology really changed that fast?
So they ran an experiment.
They brought in two groups: those who believed they were gluten intolerant, and those who didn’t.
They served everyone the same gluten-free meal—but told them it contained gluten.
The results?
People with no biological markers of gluten intolerance started reacting. Hard.
Hives. Bloating. Cramping. Diarrhea. Rashes.
But there was zero gluten. So what gives?
How could beliefs about gluten alter their physiology?
Reality leaves a lot to the imagination.
Your Brain as a Prediction Engine
A revolutionary new theory of the brain as a prediction machine explains how conscious and unconscious expectations shape our perceptions and our reality.
According to cognitive scientist Andy Clark, your brain isn’t a passive receiver. It’s an active prediction engine, constantly scanning your environment, memories, and emotional state to answer one question:
“What’s about to happen next?”
It uses your beliefs, experiences, and history to generate an answer—before anything happens.
Then it prepares your body, your emotions, and your behavior as if the prediction is already true.
Because to your brain, expectation (aka its prediction) is reality.
That’s why:
a veteran sitting in park might hear loud fireworks and get triggered into fight-or-flight even though they’re safe.
or someone can feel real pain in a limb that’s no longer there (phantom limb syndrome).
or why sugar pills can cause negative side effects (nocebo) or relieve pain (placebo) when the brain thinks the treatment is real.
In all of these, the brain is pulling from past experience, associations, and meanings to make sense of the present. But sometimes it gets it wrong.
It misreads the data in the moment.
But the body reacts anyway.
Every minute of every day, your brain is reading data and predicting your future, then adjusting your biology and your behavior to match its prediction.
These aren’t coincidences. They’re patterns.
And it isn’t dysfunction. It’s efficiency.
Your brain is making its best guesses trying to protect you with the data it has. Your beliefs and expectations are data points that shape its prediction for you.
The problem? That data is often outdated. Inherited. Absorbed. Shaped by people, experiences, or environments that no longer have anything to do with who or where you are now.

What You Expect, You Become
Most of us go about our day assuming that thoughts are just thoughts. That beliefs are purely mental. Internal. Invisible.
But science tells a different story: every belief your brain holds about your body, your environment, your limits is broadcast to your nervous system like a command.
And your biology responds.
One of the most powerful examples comes from a Harvard study on hotel cleaners. Many of these women walked over 8,000 steps a day, lifted heavy linens, scrubbed floors, essentially doing the equivalent of a daily gym workout. But when researchers asked them if they exercised, most said no.
They didn't think they were exercising. So, their bodies didn't respond as if they were.
Then one group was told that their daily work was as vigorous as a gym session and that it met the CDC’s standards for physical activity.
That single shift in framing—and nothing else—led to measurable improvements:
Lower blood pressure
Weight loss
Better body composition
Same tasks. Different expectations. Radically different outcomes.
This is the expectation effect in action: when the brain’s prediction machine gets new instructions, the whole body follows suit.
The reality we will experience tomorrow is in part a product of the mindsets we hold today.
The Silent Beliefs Shaping Your Potential
If your brain can be shaped by what you believe, it can also be shaped by what others believe about you.
In one classic study (🎬), researchers told teachers that certain students in their class were “late bloomers”—kids on the verge of a major leap in intelligence.
But the kids were randomly selected. Totally average.
But by year’s end, their IQs had increased. Not because they were smarter. Because someone believed they could be.
They were treated with more patience. Given more attention. Spoken to with belief.
And those small signals—barely perceptible—changed the trajectory of how those kids saw themselves. And how they showed up in the world.
That’s the power of belief, too.
Not just what you carry.
But what others silently hand you.
We even did this to lab rats! (🎬)
READER POLL
If you could update one belief that’s been running in the background, which would it be? |
Final Thought
Expectations are like oxygen — invisible, constant, and quietly shaping everything.
You might think you're just “not good with money.”
Or that your body always breaks down.
Or that relationships never work out.
But the thing is, your brain takes those assumptions as instructions. Not because they’re true but because they’re familiar.
And it uses them to predict what happens next — in your body, your behavior, and your choices.
This isn’t wishful thinking. It’s neuroscience.
Your beliefs don’t create magic.
But they do create patterns and those patterns shape your reality.
So the question isn’t whether your expectations are influencing you.
It’s whether they’re doing it by default… or by design.
Your brain is already shaping your future.
And even the smallest shift can change the pattern.
Every time you pause, question, and choose differently, you don’t just think new thoughts, you become someone new.
That’s not just mindset work. It’s transformation.
And I’m so here for it! 🔥💪
Shakila

P.S. Here’s the results of last week’s poll.
Q: Looking back, has empathy ever led you to make a bad decision?
🟩🟩🟩🟩⬜️ Yes, absolutely (55%)
🟨⬜️⬜️⬜️⬜️ No, it’s always been a strength (15%)
🟨⬜️⬜️⬜️⬜️ Sometimes (15%)
🟨⬜️⬜️⬜️⬜️ Hmm, not sure - never thought about it (15%)
Reader comments:
Alex: In light of what I’ve learned in this week’s newsletter, I’ll def have to reevaluate past empathetic moments. Thanks for the depth of insight!
Reply